Selected publications as corresponding author
a) A. Dimasi, A. Montoli, C. Lutti, A. Citarella, P. Ronchi, F. Castagnini, V. Mileo, G. Macetti, V. Baldelli, E. Rossi, P. Landini, D. Passarella, V. Fasano*
Stereodefined Synthesis of 3-Difluoromethyl-Benzoxaboroles: Novel Antimicrobials with Unlocked H-Bonding
Org. Lett. 2026, 10.1021/acs.orglett.5c04602
b) A. Montoli, A. Dimasi, A. Citarella, P. Ronchi, D. Passarella, V. Fasano*
Metal-free, Selective Ortho-Deuteration of N-heterocyclic Oxides
Adv. Synth. Catal. 2025, 367, e202401585
c) F. Migliano, L. Pozzi, A. Citarella, G. Macetti, L. Lo Presti, D. Passarella*, V. Fasano*
Rotational Motion in Bispidines: A Conformational Study
Org. Lett. 2025, 27, 9669
d) A. Citarella*, A. Fiori, A. Silvani, D. Passarella, V. Fasano*
Sustainable synthesis of 1,2,3-triazoles using Cyrene as a biodegradable solvent in click chemistry
ChemSusChem 2025, 18, e202402538
e) A. Dimasi, M. Failla, A. Montoli, A. Citarella, P. Ronchi, D. Passarella, V. Fasano*
First total synthesis of caerulomycin K: a case study on selective, multiple C–H functionalizations of pyridines
RSC Advances 2024, 14, 5542
f) M. Failla, G. W. Lombardo, P. Orlando, D. Fiorito, E. Bombonato, P. Ronchi, D. Passarella, V. Fasano*
Late-Stage Functionalisation of Pyridine-Containing Bioactive Molecules: Recent Strategies and Perspectives
Eur. J. Org. Chem. 2023, 26, e202300074
Full list of publications
49. A. Dimasi, A. Montoli, C. Lutti, A. Citarella, P. Ronchi, F. Castagnini, V. Mileo, G. Macetti, V. Baldelli, E. Rossi, P. Landini, D. Passarella, V. Fasano*
Stereodefined Synthesis of 3-Difluoromethyl-Benzoxaboroles: Novel Antimicrobials with Unlocked H-Bonding
Org. Lett. 2026, 10.1021/acs.orglett.5c04602
48. F. Migliano, L. Pozzi, A. Citarella, G. Macetti, L. Lo Presti, D. Passarella*, V. Fasano*
Rotational Motion in Bispidines: A Conformational Study
Org. Lett. 2025, 27, 9669
47. A. Maiocchi, M. Shevelev, Z. Boiarska, J. Estévez-Gallego, F. Bonato, P. Orlando, A. Chinosi, E. Marcone, A. Citarella, D. Horvath, M. O. Steinmetz, A. E. Prota, A. Varnek, V. Fasano*, D. Passarella*
Asymmetric Total Synthesis of (−)-Glycybridin B, a Pharmacophore Screened Candidate for Tubulin Binding
Chem. Eur. J. 2025, 31, e02228
46. L. Pozzi, A. Gotti, M. Fumagalli, A. Citarella, V. Fasano, G. Paladino, U. Ciriello, S. Princiotto, F. Annunziata, G. Martinelli, E. Sangiovanni, A. Pinto, M. Dell’Agli, D. Passarella*
Cannabizetol, a Novel Cannabinoid: Chemical Synthesis, Antiinflammatory Activity and Extraction from Cannabis sativa L
J. Nat. Prod. 2025, 88, 2451
45. A. V. Schellbach, D. R. Willcox, M. Guarnaccia, G. S. Nichol, V. Fasano, M. J. Ingleson*
Intermolecular sp3C-H Metalation of Non-Nucleophilic Brønsted Bases Using Simple Lewis Acids
Angew. Chem. Int. Ed. 2025, 64, e202512254
44. A. Montoli, A. Dimasi, A. Citarella, P. Ronchi, D. Passarella, V. Fasano*
Metal-free, Selective Ortho-Deuteration of N-heterocyclic Oxides
Adv. Synth. Catal. 2025, 367, e202401585
Selected as Featured Article
43. A. Montoli, A. Dimasi, M. Guarnaccia, A. Citarella, P. Ronchi, D. Blasi, S. Rossi, D. Passarella, V. Fasano*
Mechanistic insights into the base-mediated deuteration of pyridyl phosphonium and ammonium salts
RSC Advances 2025, 15, 870
42. A. Citarella*, A. Fiori, A. Silvani, D. Passarella, V. Fasano*
Sustainable synthesis of 1,2,3-triazoles using Cyrene as a biodegradable solvent in click chemistry
ChemSusChem 2025, 18, e202402538
Highlighted in Hot Topic: Click Chemistry
41. J. Wu, Hui Wang, H. Fang, K. C. Wang, D. Ghosh, V. Fasano, A. Noble*, V. K. Aggarwal*
Persistent Boryl Radicals as Highly Reducing Photoredox Catalysts for Debrominative Borylations
J. Am. Chem. Soc. 2025, 147, 19450
40. A. Citarella*, G. Sibille, D. Moi*, A. Dimasi, T. Braga, L. Dal Col, L. Ruberto, S. Pieraccini, M. Sironi, N. Micale, T. Schirmeister, V. Fasano, A. Silvani, C. Giannini, G. Gribaudo, D. Passarella
Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity
Bioorg. Med. Chem. 2025, 128, 118258
39. M. Pedrini, L. Pozzi, F. Sacchi, A. Citarella,* V. Fasano, P. Seneci, S. Pieraccini, L. Ruberto, H. Perez Peña, A. Garzino-Demo, A. Vitiello, L. Sernicola, A. Borsetti, A. Calistri, C. Parolin, D. Passarella*
Design, synthesis and in vitro validation of bivalent binders of SARS-CoV-2 spike protein: Obeticholic, betulinic and glycyrrhetinic acids as building blocks
Bioorg. Med. Chem. 2025, 121, 118124
38. A. Amenta, G. Nordio, F. Piazzola, M. L. Di Paolo, F. Milani, M. Giacomini, A. Citarella*, U. Ciriello, G. Paladino, S. Pellegrino, F. Silvestri, V. Fasano, L. Dalla Via*, D. Passarella
Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity
Pharmaceutics 2025, 17, 636
37. S. Borsoi, L. Pozzi, V. Fasano, A. Citarella, G. Macetti, L. Lo Presti, G. Paladino, U. Ciriello, D. Passarella*
Revisiting the Reduction of Vinpocetine
ChemistrySelect 2025, 10, e202406175
36. A. Dimasi, M. Failla, A. Montoli, A. Citarella, P. Ronchi, D. Passarella, V. Fasano*
First total synthesis of caerulomycin K: a case study on selective, multiple C–H functionalizations of pyridines
RSC Advances 2024, 14, 5542
Included in Emerging Investigators Series
35. A. Citarella*, M. Cavinato, A. Amenta, M. Nardini, A. Silvani, D. Passarella, V. Fasano*
A Green Approach to Nucleophilic Aromatic Substitutions of Nicotinic Esters in Cyrene
Eur. J. Org. Chem. 2024, 27, e202301305
Front Cover EurJOC 15/24
Part of the New-Generation Methodologies in Organic Chemistry
34. E. Bombonato, V. Fasano, D. Pecorari, L. Fornasari, F. Castagnini, M. Marcaccio, P. Ronchi*
Electrochemical Synthesis of Unnatural Amino Acids Embedding 5- and 6-Membered Heteroaromatics
ACS Omega 2024, 9, 13081
33. A. Citarella*, M. Cavinato, E. Rosini, H. Shehi, F. Ballabio, C. Camilloni, V. Fasano, A. Silvani, D. Passarella, L. Pollegioni, M. Nardini*
Nicotinic Acid Derivatives As Novel Noncompetitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment
ACS Med. Chem. Lett. 2024, 15, 1474
32. E. Colombo, D. A. Coppini, S. Borsoi, V. Fasano, R. Bucci, F. Bonato, E. Bonandi, F. Vasile, S. Pieraccini, D. Passarella*
Total Synthesis of an Epothilone Analogue based on the Amide‒Triazole Bioisosterism
ChemPlusChem 2024, 89, e202400413
31. A. Maiocchi, M. Fumagalli, M. Vismara, A. Blanco, U. Ciriello, G. Paladino, S. Piazza, G. Martinelli, V. Fasano, M. Dell’Agli, D. Passarella*
Minor Cannabinoids as Inhibitors of Skin Inflammation: Chemical Synthesis and Biological Evaluation
J. Nat. Prod. 2024, 87, 1725
30. A. Citarella*, S. Petrella, D. Moi, A. Dimasi, T. Braga, L. Ruberto, S. Pieraccini, M. Sironi, N. Micale, T. Schirmeister, G. Damia, V. Fasano, A. Silvani, C. Giannini, D. Passarella
Synthesis of α-fluorocinnamate derivatives as novel cathepsin S inhibitors with in vitro antiproliferative activity against pancreatic cancer cells
Bioorg. Med. Chem. 2024, 84, 117987
29. M. Galli, F. Migliano, V. Fasano, A. Silvani, D. Passarella, A. Citarella*
Nirmatrelvir: From Discovery to Modern and Alternative Synthetic Approaches
Processes 2024, 12, 1242
28. M. Failla, G. W. Lombardo, P. Orlando, D. Fiorito, E. Bombonato, P. Ronchi, D. Passarella, V. Fasano*
Late-Stage Functionalisation of Pyridine-Containing Bioactive Molecules: Recent Strategies and Perspectives
Eur. J. Org. Chem. 2023, 26, e202300074
Front Cover EurJOC 16/23
Voted as Readers’ choice EurJOC
Recognised as top cited article
Selected as Very Important Paper
27. A. Amenta, D. Caprioglio, A. Minassi, L. Panza, D. Passarella, V. Fasano*, D. Imperio*
Recent advances in the development of CB1R selective probes
Front. Nat. Prod. 2023, 10.3389/fntpr.2023.1196321
26. Z.-S. Wang, S. H. Bennett, B. Kicin, C. Jing, J. A. Pradeilles, K. Thai, J. R. Smith, P. D. Bacoş, V. Fasano, C. M. Saunders, V. K. Aggarwal*
De Novo Synthesis of Dihydrobenzofurans and Indolines and Its Application to a Modular, Asymmetric Synthesis of Beraprost
J. Am. Chem. Soc. 2023, 145, 14124
25. V. Fasano, R. C. Mykura, J. M. Fordham, J. J. Rogers, B. Banecki, A. Noble, V. K. Aggarwal*
Automated Stereocontrolled Assembly-Line Synthesis of Organic Molecules
Nat. Synth. 2022, 1, 902
Video of the robot in action!
Highlighted in Chemistry World
Podcasted in Solutions Science
24. A. Maiocchi, J. Barbieri, V. Fasano*, D. Passarella*
Stereoselective Synthetic Strategies to (−)-Cannabidiol
ChemistrySelect 2022, 7, e20220240
23. L. Lewis-Borrell, M. Sneha, I. P. Clark, V. Fasano, A. Noble, V. K. Aggarwal*, A. J. Orr-Ewing*
Direct observation of reactive intermediates by time-resolved spectroscopy unravels the mechanism of a radical-induced 1,2-metallate rearrangement.
J. Am. Chem. Soc. 2021, 143, 17191
22. D. P. Hari, R. Madhavachary, V. Fasano, J. Haire, V. K. Aggarwal*
Highly Diastereoselective Strain-Increase Allylborations: Rapid Access to Alkylidenecyclopropanes.
J. Am. Chem. Soc. 2021, 143, 7462
21. V. Fasano, V. K. Aggarwal*
Origin of stereocontrol in the Matteson reaction: Importance of attractive electrostatic interactions.
Tetrahedron 2021, 78, 131810
20. V. Fasano, A. W. McFord, C. P. Butts, B. S. L. Collins, N. Fey, R. W. Alder, V. K. Aggarwal*
How big is the pinacol boronic ester as substituent?
Angew. Chem. Int. Ed. 2020, 59, 22403
Selected as Hot paper
19. S. H. Bennett, A. Fawcett, E. H. Denton, T. Biberger, V. Fasano, N. Winter, V. K. Aggarwal*
Difunctionalization of C–C σ Bonds Enabled by the Reaction of Bicyclo[1.1.0]butyl Boronate Complexes with Electrophiles: Reaction Development, Scope, and Stereochemical Origins.
J. Am. Chem. Soc. 2020, 142, 16766
18. C. Jing, S. Mallah, E. Kriemen, S. H. Bennett, V. Fasano, A. L. L. Lennox, I. Hers, V. K. Aggarwal*
Synthesis, Stability and Biological Studies of Fluorinated Analogues of Thromboxane A2.
ACS Cent. Sci. 2020, 6, 995
17. V. Fasano, N. Winter, A. Noble, V. K. Aggarwal*
Divergent, stereospecific mono– and difluoromethylation of boronic esters.
Angew. Chem. Int. Ed. 2020, 59, 8502
Selected as Hot paper
Highlighted in OPRD
16. D. P. Hari; J. C. Abell, V. Fasano, V. K. Aggarwal*
Ring Expansion Induced 1,2-Metallate Rearrangements: Highly Diastereoselective Synthesis of Cyclobutyl Boronic Esters.
J. Am. Chem. Soc. 2020, 142, 5515
15. D. Kaiser, A. Noble, V. Fasano, V. K. Aggarwal*
1,2-Boron Shifts of β-Boryl Radicals Generated from Bis-boronic Esters Using Photoredox Catalysis.
J. Am. Chem. Soc. 2019, 141, 14104
Highlighted in Org. Chem. Portal
14. J. E. Radcliffe, V. Fasano, R. W. Adams, P. You, M. J. Ingleson*
Reductive α-borylation of α,β-unsaturated esters using NHC–BH3 activated by I2 as a metal-free route to α-boryl esters.
Chem. Sci. 2019, 10, 1434
13. V. Fasano, J. Cid, R. J. Procter, M. J. Ingleson*
Selective boryl–anion migration in a vinyl sp2–sp3 diborane induced by soft borane Lewis acids.
Angew. Chem. Int. Ed. 2018, 57, 13293
12. V. Fasano, M. J. Ingleson*
Recent advances in water-tolerance in Frustrated Lewis Pairs chemistry.
Synthesis 2018, 50, 1783
Invited contribution
11. M. J. Bayne, V. Fasano, M. K. Szkop, M. J. Ingleson*, D. W. Stephan*
Phosphorous(V) Lewis acids: water/base tolerant P3–trimethylated trications.
Chem. Commun. 2018, 54, 12467
10. R. J. Kahan, D. L. Crossley, J. Cid, J. E. Radcliffe, A. W. Woodward, V. Fasano, S. Endres, G. F. S. Whitehead, M. J. Ingleson*
Generation of a series of Bn fused oligonaphthalenes (n = 1 to 3) from a B1-polycyclic aromatic hydrocarbon.
Chem. Commun. 2018, 54, 9490
9. V. Fasano, J. LaFortune, J. M. Bayne, M. J. Ingleson*, D. W. Stephan*
Air– and water–stable Lewis acids: synthesis and reactivity of P-trifluoromethyl electrophilic phosphonium cations.
Chem. Commun. 2018, 54, 662
8. J. E. Radcliffe, J. J. Dunsford, J. Cid, V. Fasano, M. J. Ingleson*
N-Heterocycle-Ligated Borocation as Highly Tunable Carbon Lewis Acids.
Organometallics 2017, 36, 4952
7. V. Fasano, L. D. Curless, J. E. Radcliffe, M. J. Ingleson*
Frustrated Lewis Pair Mediated 1,2–Hydrocarbation of Alkynes.
Angew. Chem. Int. Ed. 2017, 56, 9202
6. V. Fasano, J. E. Radcliffe, M. J. Ingleson*
Mechanistic insights into the B(C6F5)3-initiated aldehyde-aniline-alkyne reaction to form substituted quinolines.
Organometallics 2017, 36, 1623
5. V. Fasano, M. J. Ingleson*
Expanding Water/Base Tolerant FLP Chemistry to Alkylamines Enables Broad Scope Reductive Aminations.
Chem. Eur. J. 2017, 23, 2217
Selected as Hot paper
Highlighted in Angew. Chem.
Highlighted in Org. Chem. Portal
4. V. Fasano, J. E. Radcliffe, L. D. Curless, M. J. Ingleson*
N–Methyl–benzothiazolium Salts as Carbon Lewis Acids for Si−H σ-Bond Activation and Catalytic (De)hydrosilylation.
Chem. Eur. J. 2017, 23, 187
Selected as Hot paper
3. V. Fasano, J. E. Radcliffe, M. J. Ingleson*
B(C6F5)3–Catalyzed Reductive Amination using Hydrosilanes.
ACS Catal. 2016, 6, 1793
2. J. R. Lawson, V. Fasano, J. Cid, I. Vitorica-Yrezabal, M. J. Ingleson*
The carboboration of Me3Si-substituted alkynes and allenes with boranes and borocations.
Dalton Trans. 2016, 45, 6060
1. A. J. Warner, J. R. Lawson, V. Fasano, M. J. Ingleson*
Formation of C(sp2)-Boronate Esters by Borylative Cyclization of Alkynes Using BCl3.
Angew. Chem. Int. Ed. 2015, 54, 11245
FasanoLAB 